Development of Ibuprofen Loaded Solid Dispersion with Improved Dissolution Using Tween 80 & Span 80

Effects of Tween-80 on the Dissolution Properties of Daidzein Solid Dispersion in Vitro

Objective Solid dispersions of daidzein (DZ) were prepared using tween-80 as the surfactant to improve its dissolution and solubility. Methods Using tween-80 as the surfactant and polyethylene glycol (PEG)-10000 as the carrier, solid dispersions of DZ were prepared by solvent method. Infrared spectroscopy (IR) and X-ray diffraction spectroscopy were applied to determine the status of DZ in carr...

Dispersion of oil into water using lecithin-Tween 80 blends: The role of spontaneous emulsification.

Lecithin-rich mixtures of the nontoxic surfactants lecithin and Tween 80 are effective marine oil spill dispersants, but produce much higher oil-water interfacial tension than other, comparably effective dispersants. This suggests interfacial phenomena other than interfacial tension influence lecithin-Tween 80 dispersants' effectiveness. The interface between seawater and dispersant-crude oil m...

The Effect of Tween 20, 60, and 80 on Dissolution Behavior of Sprionolactone in Solid Dispersions Prepared by PEG 6000.

PURPOSE Solid dispersions have been efficient in improving the dissolution rate and bioavailability of hydrophobic drugs. The aim of the present study was enhancement of the dissolution profile of Spironolactone using solid dispersion. METHODS Spironolactone solid dispersions (1:1, 1:2 and 2:1 drug: carrier weight ratio) were prepared by polyethylene glycol (PEG) 6000 as a carrier by hot melt...

dissolution rate enhancement of irbesartan using solid dispersion with pegs

The surfactant tween 80 enhances biodesulfurization.

In biocatalytic conversions, substrates and products may display inhibitory or toxic effects on the biocatalyst. Rhodococcus erythropolis 1awq could further remove sulfur from hydrodesulfurized diesel oil, and the biodesulfurization was enhanced by the surfactant Tween 80. Tween 80 was shown to decrease the product concentration associated with the cells, reducing product inhibition.